A Quora user asked recently, “What are some of the risks associated with taking high-dose Vitamin D supplements over a long period of time?” It is a valid question, particularly in India, where vitamin deficiency and self-supplementation are common. We spoke with Dr Vyankatesh Shivne, Consultant Endocrinologist and Metabolic Doctor, Department of Endocrinology at Jaslok Hospital and Research Centre in Mumbai, and Dr Vimal Phuja, Assistant Director, Internal Medicine and Metabolic physician, Dr LH Hiranandani Hospital in Powai, to clear up the confusion. DISCLAIMER : This article was based on public information and/or experts we spoke to. What is a “high dosage” and what is toxic? Vitamin D is often called the Sunshine Vitamin because it is abundant in sunlight. “India, despite being a sunny nation, is a country where most people are either Vitamin D deficient or insufficient,” says Dr Pahuja. “Normally, a Vitamin D level more than 30ng/mL would be considered a sufficient amount, as this level stabilizes the Parathyroid hormone without harming the bones.” He explains that Vitamin D levels above 100-150ng/mL can be harmful to the body. At these levels, more calcium will be excreted into the urine and this can lead to kidney stones. “Vitamin D supplements exceeding 50,000 IU daily for several weeks are toxic,” he says. According to Dr Shivane: “In India, vitamin D deficiencies are widespread, but excessive supplementation is a new concern.” The optimal serum 25(OHD)D range for bone and muscle health is 20-40ng/mL. Testing is recommended before starting supplements. Since vitamin D is fat soluble, toxicity can develop slowly and manifest as nausea, thirst and confusion. It is not always the situation, but some patients continue to take daily supplements instead of weekly. ‘How can someone differentiate between normal dehydration and the excessive thirst associated with diabetes?’How long can one safely take high-dose vitamin D?”One should take Vitamin D supplements only as per their Doctor’s advice. “Do not take these supplements longer than prescribed,” says Dr Pahuja. “One should check and confirm these levels at the earliest. In some cases, concomitant tests of Blood Calcium and Phosphorous are required to detect excess calcium in the blood.”Story continues below this adHow often should vitamin D levels be tested? It is important to confirm these levels as soon as possible. In some cases, concomitant blood tests for calcium and phosphorus are needed to detect excess calcium in the body. The sun should be able to reach the maximum surface area of the body, such as both hands below elbows and both legs below knees. It is advised not to apply sunscreen or lotions on these parts to get maximum benefit of sunlight.”DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Consult your doctor before beginning any new routine.
