Is it concerning when HbA1C increases and fasting blood glucose, or FBS, decreases? Quora asked the same question: Why are my FBS results 121 but HbA1C 4.0? We consulted an expert after receiving the first test results of 4.3 and 111. Dr Pranav Ghody is a consultant endocrinologist, and diabetologist, at Wockhardt Hospitals in Mumbai Central. He said that this may seem contradictory at first, but it’s possible. “HbA1c is your average blood glucose over the last 2 to 3 month, while fasting sugar is only one reading at a particular time.” This article is based solely on information that was obtained from public sources and/or experts. Should this be a concern? An FBS of 121mg/dL falls into the prediabetes category, so it should not be ignored. Even if the HbA1c appears to be reassuringly low, a consistently high fasting sugar can signal a glucose imbalance. It’s important not to rely solely on one measurement. Both readings will give you a more accurate picture. Dr Ghody said that this can result in higher fasting levels, even if daytime sugars are normal. This keeps HbA1c at a lower level. There are several possible reasons for this mismatch. “Lab variation and pre-test factors such as stress, late-night eating, poor sleep or illness can temporarily increase fasting glucose. In some cases, conditions affecting red blood cells like anemia or blood loss can falsely lower HbA1c. This makes it appear better than it is. It’s important to understand the numbers in context,” explained Dr Ghody. Here’s what you need to consider (Photo: Qora). What to do?Repeat the tests to confirm patterns. ‘Can diabetics consume small amounts of sugar occasionally without causing harm to their blood glucose levels?'”Focus on lifestyle basics: balanced meals, early dinners, good sleep, and stress management, as these can greatly affect fasting glucose. If the pattern persists, a detailed analysis can help determine the root cause and guide you to the best approach,” said Dr Ghody.DISCLAIMER This article is based upon information that was obtained from the public domain or experts we spoke with. Consult your doctor before beginning any new routine.