After a week of surprise and intrigue, Week 2 of the NFL kicks off with a full 16-game slate, including several key divisional matchups. Among the more intriguing is an NFC East clash between the Washington Commanders and Dallas Cowboys (-3.5) on Sunday afternoon in a contest with the highest O/U (50.5) on Sunday. It’s one of five divisional matchups of the week. Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades:
Week 2 ends with a ‘Monday Night Football’ matchup between the New York Giants and the Los Angeles Rams (-7.5). The Giants opened with a stunning 28-20 win over the Cowboys, while the Rams were dominated in a 27-7 loss to the 49ers in Melbourne, Australia. Sunday’s largest spreads include Dolphins vs. 49ers (-13.5), Browns vs. Buccaneers (-8.5) and Saints vs. Ravens (-8.5). The smallest spreads in Week 2 include Panthers vs. Falcons (+2.5), Jaguars vs. Broncos (-2.5) and Texans (-2.5) vs. Bengals.
Before making any Week 2 NFL picks or NFL score predictions on those games or others, you need to see the NFL against the spread, over/under and money line predictions powered by the self-learning SportsLine AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team’s historical data and then quantitatively evaluating the strength of the opponent’s defense by assigning a numeric value out of 100 called a matchup score. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines at NFL betting sites, and has hit thousands of 4.5- and 5-star prop picks since the start of the 2023 season.
For Week 2, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 2 NFL schedule here.
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Top Week 2 NFL AI picks
After analyzing every game in Week 2, SportsLine AI is projecting a 24-18 win for the Packers against the Jets. After a meltdown in Minnesota, Green Bay will look to get back on track and avoid an 0-2 start to the season. Quarterback Jordan Love threw for 387 yards and two touchdowns in the 39-22 loss at Minnesota.
New York, meanwhile, is coming off a 23-10 win over Tennessee. The Jets outgained the Titans 367-195 en route to the win. SportsLine AI rates the Under (44.5) in Packers vs. Jets as an A-level pick. With the spread currently at Packers (-3.5), Green Bay is the better value for ATS picks. See its other Week 2 football predictions and football picks at SportsLine.
How to make Week 2 NFL picks
In addition, SportsLine AI has generated several other A+ picks that you needed to see. You need to see the AI’s NFL picks before making any Week 2 NFL bets of your own. You can only see them at SportsLine.

A military flyover took place Friday afternoon over Oxford’s iconic Square ahead of Saturday’s matchup, when Ole Miss will welcome Lane Kiffin back to campus in a game 10 months in the making.
Fans streamed through the area, buying up Ole Miss gear while making stops within local restaurants to kick their weekend off.
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There is nothing quite like Oxford, Mississippi, from its Southern charm to the small-town feel that defines it. An estimated 300,000 people are expected on campus today, with most of them partying in “The Grove” like it’s going out of style.
LANE KIFFIN’S RETURN TO OLE MISS COMES WITH BETRAYAL, LAWSUITS AND MEMORIES OF HIM TRYING TO BURN IT ALL DOWN ON WAY TO LSU
The truth is, fans have had this weekend circled for 10 months.
Ole Miss faithful are going to try to unleash nearly a year’s worth of aggravation over 24 hours, hoping to party into the early morning hours Sunday — or at least until local police kick them out around 1 a.m. CT — regardless of the outcome.
Scenes that look more like something out of a John Grisham thriller tucked away in a small Mississippi town, it’s not hard to notice how much this means to a fan base that has been put through the ringer over these past 10 months.
‘HE’S DUST’: OLE MISS STUDENTS RIP LANE KIFFIN AS LSU COACH PREPARES FOR HATRED IN OXFORD
In reality, they have a team capable a competing for a national championship this season. But first, they have a lot to get off their chest when it comes to their former head coach, Lane Kiffin.
Lane Kiffin knows he tarnished his reputation. But, he also embraces villain role
A man who captivated a fan base, led them to heights rarely achieved and had them finally in the college football playoff after fumbling the opportunity in 2025, left them for a better job.
But, it was how he left Ole Miss that will forever tarnish his legacy in Oxford. This, along with trying to take nearly every star on the Rebels football team, left fans with a worse feeling than had he just bolted for LSU without trying to burn it all down on the way out.
Looking back, Lane has admitted to those around him that he should have handled the entire situation better. Maybe this weekend doesn’t contain as much vitriol.
Maybe, Kiffin receives plenty of boos from the crowd, but deep down inside they are content with how things would have played out if he had chosen to act like a grown-up during the entire ordeal while contemplating whether to take the Florida or LSU job.
But, we don’t live in a “what if” world.
We live in reality, and that will be welcomed by Lane on Saturday when he walks off the bus that is tucked away inside a fenced-in area just outside Vaught Hemingway Stadium.
There is not much Ole Miss fans can say to Kiffin that he isn’t already prepared for. But, that doesn’t mean deep down inside it doesn’t bother him. As much as he loves playing the villain, he’s still just a guy who feels lost at times without his father around any longer.
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Roaming around “The Grove” on Friday afternoon, Ole Miss fans had plenty to say about their former head coach, and the guy they worshiped for nearly six years.
“Man, I’m not gonna lie bro, F— Lane Kiffin,” one Rebels fan said. “Lane Kiffin is ‘K’ bro. We smokin’ him, no cap. Whatever Lane Kiffin did, it’s bulls—. He could have waited to leave until after the season. Nah, he wanted to wait until he got us to the playoff to leave.
“F— Lane Kiffin, bro. And, f— LSU.”
Saturday in Oxford will look like an action movie, with college football pageantry
There’s no denying we are about to witness one of the more cinematic scenes in this sport’s history.
I was in Austin last weekend as Arch Manning led Texas to the comeback win over Ohio State, and I’m still amazed at what I witnessed.
But, even that monumental game does not have the built-in drama compared to what we will witness inside Vaught Hemingway Stadium.
Lane Kiffin will stroll off the LSU bus later this afternoon, acting as if none of the noise is bothering him. He will walk into a stadium that he helped revitalize, alongside a number of assistant coaches on his LSU staff that helped him do it in this same town.
On the other side, Pete Golding will receive a hero’s welcome when he takes his first steps onto the field in front of the Ole Miss student section.
It’s fitting. After the past ten months of buildup to this matchup that feels more like a heavyweight fight we used to witness in the late ’90s.
I’m fascinated to see how this plays out, alongside 60,000 fans wearing mostly powder blue and red, with a smattering of purple and gold.
We made it.
No more talking. No more jabs being traded through social media and television networks.
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All eyes will be on Oxford, Miss., during the Week 3 college football schedule as Lane Kiffin returns to The Grove. His former team in No. 8 Ole Miss will host Kiffin’s new squad in seventh-ranked LSU, as the Tigers are 3-point road favorites per the Week 3 college football odds, as LSU quarterback Sam Leavitt has been removed from the injury report after initially being listed as doubtful. This is the lone top-10 matchup one can make college football bets on this week, and each of their last six meetings have been won by the home team. Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades:
Elsewhere, there is an eclectic mix of games to target with Week 3 college football bets, including several schools beginning conference play such as No. 2 Georgia vs. Arkansas (+24.5) and No. 12 USC vs. Rutgers (+21.5). There are also non-conference battles like No. 10 Alabama vs. Florida State (+19.5) and No. 25 Virginia vs. West Virginia (+10.5). Before locking in any Week 3 college football picks, be sure to see the latest college football predictions from SportsLine’s proven model.
The model simulates every FBS game 10,000 times. It is on a 33-21 run on top-rated CFB money-line picks on betting sites since the 2024 season, and it has been upgraded for the 2026 season to even better factor in the transfer portal. Anybody following its college football betting picks could have seen strong returns.
Now, it has turned its attention to the latest college football odds for Week 3 and locked in picks for every FBS matchup. Head here to see every pick.
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Top college football predictions for Week 3
One of the top Week 3 college football picks the model is recommending for best betting apps: South Carolina (-3.5, 58.5) covers at home versus Mississippi State at 4:15 p.m. ET in nearly 60% simulations. The Gamecocks have defeated the Bulldogs in eight of their last nine meetings as this is one of the SEC’s most lopsided series over recent matchups. SC’s LaNorris Sellers has shown off his dual abilities with 270 yards and 3 touchdowns through the air in Week 1, followed by 119 yards and a score on the ground last week. South Carolina’s defense has allowed just one touchdown on the year, while Mississippi State’s defense has yet to force a turnover.
Another Week 3 prediction: Michigan State (+28.5, 51.5) stays within the huge line at No. 3 Notre Dame in a 7:30 p.m. ET kickoff on Saturday. Michigan State has won both tune-up games and is 1-0-1 against the spread with a cover against Eastern Michigan and a push against Toledo. Notre Dame has handled its business as well with two wins and as many covers.
Notre Dame beat Wisconsin by 28 points in its opener, and the Irish only have two wins of 30 or more points against Power 4 schools since the beginning of last season. The model is projecting a 46-18 final as MSU stays within the big number nearly 60% of the time, while the Over 51.5 clears 66% of the time. See which other picks the model likes here.
How to make college football picks for Week 3
The model has also made the call on who wins and covers in every Week 3 college football game, including an underdog of nearly a touchdown who wins outright in one of the week’s biggest games. You can only get every pick for every game at SportsLine.
So what college football picks can you make with confidence, and which underdog pulls off a shocking upset? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that is on a 33-21 run, and find out.
College football odds for Week 3 notable games
See full Week 3 college football picks, odds, predictions here
(odds subject to change)

CHAPEL HILL — University of North Carolina leaders emphasized this week that a recent outside investigation into its football program found only isolated incidents — signaling they have faith head coach Bill Belichick’s program doesn’t have a widespread problem of misconduct.
But UNC leaders also said they would dig into any new allegations if they arise — putting Belichick and other leaders in the program on notice.
“This investigation is closed,” UNC general counsel Paul Newton added in a briefing about the investigation, “but our door is never closed to expressions of concern about this program.”
Two of Belichick’s top lieutenants resigned amid the inquiry — his son, defensive coordinator Steve Belichick, and general manager Michael Lombardi. But the statements by UNC leaders and their outside investigators offered few specifics about the investigation or whether the resignations were even connected to the probe, which included questions about allegations of drug use and in appropriate relationships.
“The investigation determined that certain actions demonstrated a disregard for Carolina’s values and standards of conduct,” UNC said in its statement Thursday. “The investigation also found that these actions were isolated in scope and not a systemic failure.”
Nevertheless, the university managed to send a clear message to governing bodies that have the power to investigate and penalize universities over compliance issues, according to legal analysts.
“What they’re acknowledging in this [statement], which is using as little information as possible, is that, ‘We’ve taken care of this,’ essentially, ‘and so, outside regulatory bodies, we’re handling this as an institution and if you need to know anything, we’ll communicate that to you,’” said Jason Montgomery, a former NCAA investigator who is now a partner at law firm Husch Blackwell in Kansas City.
During the course of the inquiry, investigators asked interviewees the culture of the football program under Bill Belichick, raising some speculation about whether the probe could affect his status with the program. His contract requires him to “promote an atmosphere of compliance” and to maintain institutional control in the program, ensuring that rules and policies of the university, NCAA and ACC are followed — and that potential violations are reported. The contract also says he’s responsible for the conduct of his assistant coaches and other program employees.
Belichick said this month that his team maintains an environment of compliance and that he understood the importance of the investigation into his football program and the “high standard here of our code of conduct and doing things the right way.” Investigators said Belichick was cooperative and open during the inquiry.
“Everybody’s responsible, including me, for doing things properly, and we intend to do that,” Belichick said during a Sept. 7 news conference. He added: “We want to run the program in the very best way, and if there’s things we need to do to correct it, then we’ll obviously do them.”
It was unclear whether the NCAA would investigate UNC following its internal probe. “Due to confidentiality rules put in place by member schools, the NCAA does not comment on current, pending or potential investigations,” a spokeswoman said in a statement to WRAL. The College Sports Commission, another regulatory body, likewise said it doesn’t comment on the existence of investigations.
“While the investigation has concluded, our commitment to receiving and addressing concerns is not over,” Newton said. “One hallmark of a great culture is a culture that encourages [and] rewards expressions of concerns anybody has at any time, and we are going to have that culture in this football program. People will know that they know they can raise their hand and express their concern without any fear of retaliation, and we will take all concerns seriously and we will act on those that are credible.”
‘The dreaded hammer’
If an NCAA program is found to have lost institutional control, it could face major penalties or probation. So universities seek to assure the NCAA and other bodies that, in the face of scandal, they maintain control, legal analysts said.
“The dreaded hammer from the NCAA is a [finding of] lack of institutional control … which means an overall failure to monitor the football program in a way so that it will operate consistently with the rules,” said J. Andrew Fine, a Durham lawyer who represents athletics-related clients.
Investigators who carried out the UNC probe asked interviewees about whether Steve Belichick had used drugs on the job or if had given drugs to at least one player, people familiar with the investigation previously told WRAL. Lombardi faced a one-game suspension this season for a self-reported NCAA violation involving off-campus recruiting, internal documents obtained by WRAL show. Neither man has responded to multiple requests for comment.
Based on what the university has said about the investigation — characterizing it as an institutional issue and referencing university policies and standards versus NCAA rules — indicates that UNC is treating this more as an internal human resources case and less a case for an outside regulator, Montgomery said.
The resignations and a separate suspension this week of a player who faces a gun charge after a traffic stop happened in a span of two weeks. They’re among a broader tapestry of distractions that have befallen the program, including allegations of a divided locker room, questions about the influence Bill Belichick’s girlfriend has over his media projects, a spate of traffic citations and parking complaints against players, and the suspension of an assistant coach that coincided with a memo reminding members of the program that selling complimentary tickets could violate NCAA rules. There was also a smattering of self-reported minor NCAA violations last year.
And while many of those incidents might be considered one-offs, those kinds of things can add up to something bigger, Fine said.
“These little elements also go to [Bill Belichick’s] supervision of the football team,” he said. “The supervision of the football team is something that’s solely his responsibility. So whether these are isolated incidents or not, they speak to a possible lack of supervision that allowed these things to continue. That lack of supervision can certainly be held against him if they want to try to fire him for cause.. … The question just becomes whether or not they have to pay his payout that’s specified in his contract.”
Vote of confidence
Bill Belichick’s contract is worth $50 million over five years, though only the first three years and $30 million are guaranteed. If UNC decided to fire Belichick without cause, the university would owe him everything he was set to earn up until Dec. 31, 2027. If it were to fire him after finding cause for termination, the university wouldn’t be on the hook for any salary, bonuses or supplemental income after termination.
But Fine reads UNC’s messaging as a vote of confidence in the head coach, who was hired in late 2024 to elevate the program.
“What it signals is at least an attempt going forward to keep Bill Belichick around longer and help insulate him from these incidents that have occurred or that UNC has uncovered,” Fine said.
Belichick, an NFL coaching legend, won six Super Bowl championships with the New England Patriots. People familiar with his time there are surprised to see the cacophony of distractions facing the program during his time in Chapel Hill.
In New England, Belichick was known for being a focused, details-oriented coach who was keenly aware of everything that was happening within the Patriots organization. He ran a no-nonsense, no-distractions team, said Kyle Arrington, a former Patriots cornerback who won a Super Bowl with Belichick in 2014.
“One of the first philosophies Bill generally has is he wants to have the most mentally tough team and the most prepared team,” Arrington told WRAL. “So just knowing Bill, I know that the more that we’re talking about this, you know, that’s the less that they’re actually game planning to talk about football.”
Whether the distractions affect performance on the field remains to be seen. The Tar Heels (2-0) visit Clemson (1-1) on Saturday. UNC hosts No. 3 Notre Dame on Oct. 3 and three other teams currently ranked in the top 25 later in the season. Through two games, the Tar Heels have displayed an improved offense and a stout defense, appearing improved from last year’s 4-8 squad.
“The future of Bill Belichick depends on winning,” Fine said, “and the reason for that is because today college athletics is so dependent on the largess of very rich, outside donors to donate to things like name, image, likeness to help the players get paid. And what these people want to see are wins.”
He added: “The people who want to see UNC be successful also don’t want to see this kind of chaos in the program. … They don’t want to see losses on top of that, and when you combine those two things, it’s going to create a very hot seat for Bill Belichick.”

OXFORD, Miss. — Ole Miss fans have been waiting for this game since Lane Kiffin left town 10 months ago for LSU, so one more day won’t hurt. But that doesn’t mean the animosity toward their former head coach in Oxford has to simmer down before kickoff.
It took me around five minutes of traversing campus to start hearing the banter about the guy who used to roam the Rebels’ sidelines for six years.
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As he makes his way back to Oxford on Saturday afternoon to lead his Tigers into hostile territory, it’s pretty obvious that a large percentage of the fan base still holds a grudge for the way in which Lane Kiffin bolted town after Thanksgiving last year, and just two weeks before the College Football Playoff was set to begin.
LANE KIFFIN’S RETURN TO OLE MISS COMES WITH BETRAYAL, LAWSUITS AND MEMORIES OF HIM TRYING TO BURN IT ALL DOWN
“Man, I’m not gonna lie. F— Lane Kiffin. Lane Kiffin’s ‘K’, we smokin him bro, no cap,” one Ole Miss student said inside “The Grove” on Friday afternoon.
He wasn’t alone in his thoughts, as you could imagine around the Ole Miss campus.
“Man, he’s dust,” another Ole Miss student exclaimed. “He’s nothing but dust. He’s defiantly scheming, he knows what he’s doing, whether that’s putting Leavitt on the injury report, he’s f—ing playing. He’s just a scumbag.”
Oxford is buzzing with excitement ahead of Kiffin’s return and Top-10 showdown
On a beautiful, but hot, Friday afternoon in Oxford, fans flooded the historic Square located in the middle of downtown Oxford for some good eats and drinking.
The party atmosphere started on Wednesday night, and I don’t imagine this thing comes to an end until sometime Sunday afternoon. No matter what takes place on the field inside Vaught Hemingway Stadium on Saturday evening, LSU head coach Lane Kiffin will be at the forefront of a hostile environment.
At this point, fans were expecting nothing less.
MOUNTED POLICE, EXTRA PATROLS AND KIFFIN HATE: OXFORD PREPARES FOR OLE MISS-LSU GAME WITH EXTRA SECURITY
Months of talking through social media, Vanity Fair, podcasts and interviews, Lane Kiffin is clearly enjoying the attention that he’s garnering before this showdown with his former team.
And, if any one thinks different, you don’t know Kiffin. Think of it as a professional wrestler drawing boos from a crowded arena. Now, think of Lane playing the role of Hulk Hogan’s NWO persona.
Everything is a show, and Kiffin is selling advertisement for his return to Oxford.
Think about what took place earlier this week when the LSU head coach put Sam Leavitt on the initial injury report, listing him as ‘doubtful’, before upgrading him to ‘questionable’ on Thursday evening.
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Ole Miss head coach Pete Golding wasn’t buying it, not for one minute.
“Well, I got the text before the report went out from Lane, like ‘Hey, our quarterback’s out,'” Golding mentioned to Pat McAfee. “I’m like, ‘Ok buddy, I bet he is.’ I’ve been around here a lot of Wednesday’s with you man for three and half years. I said, I think our first one had 42 guys on the first ever SEC injury report on a Wednesday.
“So, I was like, ‘Yea man, see ya Saturday.'”
There will be trash talking that takes place on Saturday that would make a standup comedian blush.
Most of it will be directed at Lane Kiffin, while LSU fans will undoubtedly take some of the heat on deflection.
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But, this is what makes college football so great. A wild day around the campus of Ole Miss awaits, along with the official arrival of the most hated man in the state of Mississippi.