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Before you try vegan PDRN, heres what experts want you to know

Before you try vegan PDRN, heres what experts want you to know


Before Polydeoxyribonucleotide (PDRN) or the salmon DNA-derived ingredient, as we popularly know it, managed to get a firm footing in beauty’s hall of fame, it had humble beginnings in wound healing. Its sudden trajectory from a niche Korean treatment to being a favourite of celebrities like Jennifer Aniston, Hailey Bieber and Miley Cyrus is down to its immense benefits. But as it grows in popularity and form – from injectables to topical options and now vegan ones – does its effectiveness and by that, its very credibility, change? We ask the experts.

What is PDRN?

More often than not, you would have heard of PDRN being referred to as the ‘salmon sperm’ ingredient. That’s a bit of an oversimplification. Traditional PDRN consists of DNA fragments extracted mainly from the sperm cells of specific salmon species, such as steelhead trout or chum salmon, which then undergo extensive purification.

Basically, the ‘sperm facial’ you hear so many enthusiasts raving about is a mix of purified polydeoxyribonucleotides that are injected into the skin with tiny needles. Given that salmon DNA is similar to human DNA, PDRN is biocompatible with the human body. art from injectables, PDRN is also available in topical formulas, both traditional and plant-based.

What benefits can you actually expect from PDRN?

The proof is in its popularity, it would seem, and it does have science to back it up. “PDRN has a more serious clinical background than some beauty trends because it was primarily used in tissue repair and healing, for its ability to support cell repair, to create new blood vessels and to reduce or modulate inflammation through different pathways within the tissues. So, since it had a credible repair story in medicine, of course skincare and skin injectables became interested in the same process,” explains Dr Swetha Dilip, aesthetic physician at the White Door.​

As for whether it delivers, Dr Yash Mehta, facial plastic surgeon and founder of Aesthetic & Cosmetic Surgery (ACSC), says he genuinely sees healthier skin. “The science behind its regeneration is real; the marketing around it can sometimes become exaggerated. PDRN can definitely improve skin quality and recovery.” His patients report better hydration, smoother texture, reduced sensitivity and better recovery. “But what it does not do is replace treatments for laxity, facial volume loss, pigmentation or major textural concerns,” he adds.

Who should use PDRN

At its very core, Dr Madhuri Agarwal, founder and director of Yavana Skin & Hair Clinic, believes that PDRN is a “recovery ingredient rather than an aggressive corrective active. Unlike retinol, which pushes skin cells to turn over faster, PDRN supports the skin in repairing and rebuilding itself.” She finds it most beneficial for people dealing with early ageing, dullness, compromised skin barrier, dehydration, post-procedure recovery or skin that heals slowly. “It’s particularly useful for patients in their 30s and beyond because natural regenerative activity declines with age. It can also help younger individuals who live in polluted cities, those who have stressed skin or struggle with inflammation after acne,” she says. “PDRN is not going to erase pores, completely remove wrinkles or transform severely damaged skin on its own. One of the biggest mistakes I see is people expecting PDRN alone to replace proven skincare basics or medical treatments.”

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Fashion

The problem with wanting Cocktail 2 to be a lesbian love story so badly

The problem with wanting Cocktail 2 to be a lesbian love story so badly


It’s not hard to speculate where this rumour could have originated from and why people are so enthusiastically running with it. It has become deceptively easy to run PR campaigns surrounding upcoming films, using them to stir cultural discourse. Even though Cocktail 2 director Homi Adajania has said there is a good reason behind Sanon’s now-viral ‘threesome’ dialogue from the trailer, what is more interesting is what these conversations reveal about us as a film-going audience. Films like Kabir Singh and Animal, and in the more recent past, Dhurandhar and Tere Ishk Mein, have created the kind of celluloid landsce that mainly swings between masculine hero-worship and trite rom-coms. If two girls in a movie aren’t fighting for the affection of the lone male protagonist and Bollywood is still years away from perfecting genuine female friendships on-screen, the only option is for the audience to brand them as lesbians.

Despite the history of queerness in India spanning centuries, mainstream culture has rarely paid its due to non-heteronormative stories. Since the decriminalisation of Section 377 in 2018, the queer films we have gotten have been few and far between, with Badhaai Do delving into the lavender marriage between a gay cop and a lesbian PE teacher, Ek Ladki Ko Dekha Toh Aisa Laga a Punjabi woman (Sonam Koor)’s coming-out story, ‘Geeli Pucchi’ from Ajeeb Daastaan following an intercaste lesbian love story, and Chandigarh Kare Aashiqui centring the romance between a cisgender man and a transwoman (minus points casting Vaani Koor in the role) being the last few attempts.

Within mainstream culture, the lesbian still exists as a caricature to titillate the male gaze, never as an autonomous individual. Recently, Accused (2026), a film about a successful gynaecologist (Konkona Sen Sharma) facing anonymous allegations of sexual misconduct, explored the fetishistic accusations that lesbians are often slammed with for living their truth and how easily they can be turned into predators when the stigma surrounding their sexuality is weonised against them. A nuanced portrayal like that could have benefitted from a wider theatrical release, but there’s a real chance that it would not have been given the CBFC greenlight for ‘defiling Indian culture’ by showing a married Indian lesbian couple. When Deepa Mehta’s Fire released in 1996, it had passed through the censor board with no cuts. Only once it reached the masses did right-wing political parties call for a ban against the “immoral and pornogrhic” film, saying it went “against Indian tradition and culture”. Theatres were vandalised, cinema-goers were threatened. Despite the fact that Fire released 30 years ago, it is still hailed as one of the most progressive portrayals of sphic love to ever come out of Indian cinema.

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Fashion

Antique temple jewellery Id wear as a bride—and a Vogue editor

Antique temple jewellery Id wear as a bride—and a Vogue editor


What makes antique temple jewellery so special?

In school, I trained in Bharatanatyam. Serious dancers often arrived adorned in gleaming oddiyanams (belts), elaborate nethi chuttis (hair ornaments) and the unmistakable sun and moon-shed hair pins that transformed young girls into celestial goddesses. I gave up dancing, but my yearning for these mythological jewellery styles continued. As a South Indian—equal parts Tamil and Malayali, raised in Karnataka—who grew up surrounded by gold shops, displays featuring antique temple designs lured my mum and I more than diamonds ever could.

Originally crafted by artisans who melted down offerings made to deities, temple jewellery carries centuries of devotion within its ornate forms. After trickling down temple idols via meticulously made replicas, these ornaments eventually found their way into the bridal wardrobes of women across South India. The Kanjeevaram sari’s jewellery counterpart. Inspired by temple architecture, the designs feature miniature sculpted deities, flora and fauna in antique-finish gold. Regal, deeply symbolic and unologetically maximalist, for me, temple jewellery will remain the first purchase of my bridal trousseau I will make…when, then.

1. The oddiyanam, the golden cinch

The oddiyanam—a waist belt— is one temple jewellery style that is passed down as inheritance in South Indian families. Also known as an vaddanam in Telegu or kamarband in Hindi, it accentuates a sari’s pleats, transforming its silhouette. These often feature sculpted motifs of Goddess Lakshmi, rows of kemp stones and intricate repoussé work.

2. Stacked necklaces that reach the waist

Nothing says South Indian bride quite like stacking temple jewellery necklaces—starting with the shortest choker and extending down to the waist. This stack can include manga (mango) or kassa (coin) malai, or a mix of all. “Is she even a bride if she does not look like a Thrissur annai,” is a joke that loosely ctures the grandiosity of a bride from Kerala, comparing her to the majestic elephants at the Trissur Pooram festival.

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Fashion

Madhuri Dixit Nenes Mayyur Girotra sari is for those who want to drape their jeans

Madhuri Dixit Nenes Mayyur Girotra sari is for those who want to drape their jeans


Madhuri Dixit Nene’s wardrobe is a case study in making Indian wear look statement. Currently on a spree, delivering one strong look after another on the promotional tour for her latest movie, the actor turned to a ubiquitous fabric for an off-kilter look. Dixit Nene chose a pre-dred sari by Delhi-based designer Mayyur Girotra made with denim and a silk tissue blouse that deserves a second look.

The metallic blouse and the pre-pleated pallu were resplendent with embroidered floral pliqué. Those with a discerning eye can spot the return of modest blouses –like the high-neck and elbow-sleeve version seen on Dixit Nene here– that are still impactful.

For accessories, stylist Sukriti Grover paired the sari look with chandbali earrings, stacked gold bangles and a temple jewellery ring from label Motifs by Surabhi Didwania. She also added a handcrafted bag by Mumbai-based accessories deisgner Meera Mahadevia. Hair and makeup artists Sheetal F Khan and Shefali Sharma styled her hair in loose waves and kept the overall makeup subtle for beauty.

From Vogue’s fashion desk:

“Trust Madhuri Dixit to make a denim sari look elegant. The embroidery on the sari and the contrast silver blouse make the denim work as a sari. If you are choosing a similar denim sari or crafting one, pair it with a simple white tank or crop top and sneakers for an easy, everyday look,” says Divya Balakrishnan, Vogue India fashion associate.

Also read:

From gharchola to co-ords, bandhani is finding a life beyond weddings and festive wear

Madhuri Dixit Nene’s sari was naturally dyed with discarded marigold flowers

5 shoe trends from the ’80s to add to your wardrobe

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Fashion

At Vogue Wedding Ateliers Evening with the Editor in Mumbai, legacy came dressed in red, emeralds and heirloom diamonds

At Vogue Wedding Ateliers Evening with the Editor in Mumbai, legacy came dressed in red, emeralds and heirloom diamonds


The evening’s jewellery partner, GoluBhai Badalia Diamond, brought its own three-generation history into the room. Known for its focus on high-quality stones and careful selection, the brand sat naturally within the evening’s wider conversation around legacy. Across the room, fine jewellery peared in sharply different combinations: gold medallions over black necklines, antique pearls with linen, solitary diamonds against paillettes and sphires worn with navy embroidered saris. Elsewhere, emerald necklaces were worn with green gowns. Across the evening, inherited and fine jewellery was no longer confined to expected weddingwear pairings. It moved through black evening looks, embroidered saris, linen separates and gowns with much greater range.

For Jaya Raheja, legacy came into focus through a piece she still wears: her grandmother’s diamond solitaire pendant, given to her at her wedding. Her answers elsewhere made clear that her own bridal instincts still tilt traditional. “For me, a wedding is always going to be red,” she said, describing her ideal look as “a traditional red lehenga or a sari.” When asked about jewellery, she was equally certain. “Emerald for me,” she said, adding that she prefers a single statement piece. Her response gave the evening one of its clearest ideas: inheritance still matters, but so does the edit each person brings to it.

That tension between recognisable bridal codes and more individual styling choices returned elsewhere in the room. Makeup artist Shradha Luthra described her bridal proach as “minimal magic”, adding that brides now want to look like themselves, just “a little more enhanced”. She also pointed to the return of red this season, a shift that echoed Raheja and suggested that older bridal references are being revisited with a different sensibility rather than simply repeated.

Other guests spoke about legacy through adtation as much as inheritance. Filmmaker Himanshu Patel described the modern Indian wedding in one word as “reinvention”, arguing for “a modern touch” to old traditions. His answer widened the conversation beyond objects. Legacy, in this version, depends not only on what is handed down, but on how people continue to use it, wear it and revise it.

By the end of the evening, Mumbai offered a view of wedding style that treated legacy as something living rather than static. It could be found in diamond pendants passed down through family, in red bridal dressing returning to favour, in heritage jewels worn with newer silhouettes and in the confidence to proach all of it with a more personal point of view.

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Fashion

Karisma Kapoor elevated a simple shirt dress with a tie

Karisma Kapoor elevated a simple shirt dress with a tie


No one does androgyny better than Karisma Koor. This week, for promoting her upcoming neo-noir psychological thriller web series Brown, the actor chose a from simple shirt dress Echo Studio. However, it was the addition of the custom tie that elevated it to newer heights.

Crafted in poplin, the oversized shirt dress features ruched details on the sides that add she to the relaxed silhouette. The tie in question is a custom creation hand-embroidered with the series’ title, and is by the Noida-based label Baraamda. when it came to accessories, celebrity stylist Manisha Melwani kept things simple with silver studs from Soni Studio and rings from Kiru. The addition of square-toe shoes from Theater brought the androgynous look together.

For beauty, makeup artist Divya Shetty kept the look minimal with tinted pink lips and defined lashes while hair stylist Radhika Patel turned to a chic bun.

From Vogue’s fashion desk:

“Karisma Koor shows us a fun way to incorporate a tie into your look. Like her stick to a neutral or monochromatic silhouette, add a tie to a shirt dress that gives it some balance. The length of the tie really shes the look, go for a midi length to cut your proportions better. Pair with brogues and a great pair of sunglasses to finish your look,” says Divya Balakrishnan, Vogue India fashion associate.

Also read:

Karisma Koor layered black silk separates with an embroidered Anita Dongre jacket

Karisma Koor’s rust kurta set places intricate marodi, gota and sequin embroidery at the forefront

Karisma Koor’s Payal Khandwala kurta set brings a lighter touch to occasion wear

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